+86-13524779951 sales@xmobio.com
Products
  BIOACTIVE COMPOUND
  Anti-tumor series
  Antithrombotic series
  Anti-HCV series
  Rheumatism series
  Anti-diabetic series
  Nervous system series
  Others
  intermediate
  Featured products
  Others

This product is in stock,please ask for price.
If you have any question, please send the email to sales@xmobio.com for the availability.We will reply to you as soon as possible.
Shipment: Products are shipped via FedEx Express.
Products
Description
Danusertib, also known as PHA-739358, is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Aurora kinase inhibitor PHA-739358 binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed. This agent may preferentially bind to and inhibit Aurora B kinase. Aurora kinases, a family of serine-threonine kinases, are important regulators of cellular proliferation and division. 
Chemical Structure
 
Chemical Name
N-[5-((2R)-2-Methoxy-2-phenylethanoyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide 
SMILES Code
O=C(NC1=NNC2=C1CN(C([C@H](OC)C3=CC=CC=C3)=O)C2)C4=CC=C(N5CCN(C)CC5)C=C4 
Theoretical Analysis
XingMo Cat#:XM117 
Product Name:Danusertib (PHA-739358) 
Synonyms:PHA739358; PHA-739358; PHA 739358; Danusertib. 
CAS#:827318-97-8 
Chemical Formula:C26H30N6O3 
Exact Mass:474.23794 
Molecular Weight:474.55 
Technical Data

Appearance: white solid powder         

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

Tel: +8613524779951  QQ: 点击这里给我发消息
Email: sales@xmobio.com   Web: www.xmobio.com  沪ICP备17047952号-1
Copyright 2017 Shanghai xingMo Biotechnology Co., Ltd. All rights reserved. Supported by www.hxchem.net