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Description |
GDC-9545, also known as RG6171, is a SERD. GDC-9545 is an orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD GDC-9545 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. |
Chemical Structure |
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Chemical Name |
3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol |
Theoretical Analysis |
XingMo Cat#:XM790 Product Name:Giredestrant,GDC-0945 Synonyms:Giredestrant,GDC-0945,GDC0945 CAS#:1953133-47-5 Chemical Formula:C27H31F5N4O Exact Mass:522.2418 Molecular Weight:522.564 Purity:98%
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Technical Data |
Appearance: solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)
Solubility: Soluble in DMSO, not in water
Shelf Life:
>2 years if stored properly.
Drug Formulation:
This drug may be formulated in DMSO
Stock Solution Storage:
0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months). |
WARNING: This product is for research use only, not for human or veterinary use
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