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Description
ARRY-382 is a small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; cFMS) with potential antineoplastic activity. cFMS tyrosine kinase inhibitor ARRY-382 binds to and inhibits the activity of cFMS. By preventing colony-stimulating factor-1 (CSF-1)-cFMS signaling, this agent may inhibit tumor cell proliferation in cFMS-overexpressing tumor cells. 
Chemical Structure
 
Chemical Name
N-(3-cyclopropyl-l-((6-methylpyridin-2-yl)methyl)-lH-indazol-4-yl)-7-(2-(4- methylpiperazin-l-yl)ethoxy)imidazo[l,2-a]pyridine-3-carboxamide 
Theoretical Analysis
XingMo Cat#:XM783 
Product Name:ARRY-382 
Synonyms:ARRY-382, ARRY382 
CAS#:1313407-95-2 
Chemical Formula:C32H36N8O2 
Molecular Weight:564.69 
Purity:>98% 
Technical Data

Appearance: solid powder         

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months).

 



WARNING: This product is for research use only, not for human or veterinary use

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