This product is in stock，please ask for price.
If you have any question, please send the email to sales@xmobio.com for the availability.We will reply to you as soon as possible.
Shipment: Products are shipped via FedEx Express. |
|
| Description |
| Empesertib, also known as BAY1161909, is an orally bioavailable, selective inhibitor of the serine/threonine monopolar spindle 1 (Mps1) kinase, with potential antineoplastic activity. Upon administration, the Mps1 kinase inhibitor BAY1161909 binds to and inhibits the activity of Mps1. This causes inactivation of the spindle assembly checkpoint (SAC), accelerated mitosis, chromosomal misalignment, chromosomal missegregation, mitotic checkpoint complex destabilization, and increased aneuploidy. This leads to the induction of cell death in cancer cells overexpressing Mps1. |
| Chemical Structure |
 |
| Chemical Name |
| (R)-2-(4-fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide |
| SMILES Code |
| O=C(NC1=CC=C(C2=CN3C(C=C2)=NC(NC4=CC=C(S(=O)(C)=O)C=C4OC)=N3)C=C1)[C@H](C)C5=CC=C(F)C=C5 |
| Theoretical Analysis |
XingMo Cat#:XM740
Product Name:Empesertib
Synonyms:BAY1161909; BAY-1161909; BAY 1161909; Empesertib, Mps1-IN-5.
CAS#:1443763-60-7
Chemical Formula:C29H26FN5O4S
Exact Mass:559.169
Molecular Weight:559.6164
Purity:>98%
|
| Technical Data |
Purity:
>98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility:
Soluble in DMSO, not in water
Shelf Life:
>2 years if stored properly
Drug Formulation:
This drug may be formulated in DMSO
Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
|
WARNING: This product is for research use only, not for human or veterinary use
|
|
|
