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| Description |
| Relebactam, also known as MK-7655, a potent and selective β-lactamase inhibitor. At a concentration of 4 mg/L, MK-7655 reduced imipenem MICs for Enterobacteriaceae with KPC carbapenemases from 16-64 mg/L to 0.12-1 mg/L. MK-7655 potentiated imipenem against Enterobacteriaceae with KPC carbapenemases or combinations of β-lactamase and impermeability, but not those with metallo-carbapenemases. It augmented the activity of imipenem against P. aeruginosa in general and OprD mutants in particular |
| Chemical Structure |
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| Chemical Name |
| (1R,2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate |
| SMILES Code |
| O=S(O)(ON1[C@]2([H])CC[C@@H](C(NC3CCNCC3)=O)[N@@](C2)C1=O)=O |
| Theoretical Analysis |
XingMo Cat#:XM735
Product Name:Relebactam
Synonyms:MK-7655; MK 7655; MK7655; Relebactam
CAS#:1174018-99-5
Chemical Formula:C12H20N4O6S
Exact Mass:348.1104
Molecular Weight:348.37
Purity:>98%
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| Technical Data |
Appearance:
White to off-white solid powder
Purity:
>98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility:
Soluble in DMSO and water
Shelf Life:
>2 years if stored properly
Drug Formulation:
This drug may be formulated in DMSO or water
Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
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WARNING: This product is for research use only, not for human or veterinary use
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