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Description
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, CC-90003 inhibits ERK activity, and prevents the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival. 
Chemical Structure
 
Chemical Name
N-{2-[2-(2-Methoxy-5-methyl-pyridin-4-ylamino)-5-trifluoromethyl-pyrimidin-4-ylamino]-5-methyl-phenyl}-acrylamide 
Theoretical Analysis
XingMo Cat#:XM723 
Product Name:CC-90003 
Synonyms:CC-90003,CC90003 
CAS#:1621999-82-3 
Chemical Formula:C22H21F3N6O2 
Exact Mass:458.44 
Molecular Weight:458.17 
Purity:>98% 
Technical Data

Appearance: solid powder         

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months).

 



WARNING: This product is for research use only, not for human or veterinary use

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