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Description
Molidustat, also known as BAY 85-3934, is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells. Phase I data have shown that inhibition of HIF-PH by Molidustat results in an increase in endogenous production of EPO. Molidustat is currently clinical trials at Bayer for the treatment of patients suffering from renal anemia due to chronic kidney disease. 
Chemical Structure
 
Chemical Name
2-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-3(2H)-one 
SMILES Code
O=C1N(C2=NC=NC(N3CCOCC3)=C2)NC=C1N4N=NC=C4 
Theoretical Analysis
XingMo Cat#:XM273 
Product Name:Molidustat 
Synonyms:BAY 853934; BAY-853934; BAY853934; Molidustat. 
CAS#:1154028-82-6 
Chemical Formula:C13H14N8O2 
Exact Mass:314.12397 
Molecular Weight:314.3 
Purity:>98% 
Technical Data

Appearance: Solid powder                      

Purity:>98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

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