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Description
Doramapimod, also known as BIRB-796, is a member of the N-pyrazole-N’-naphthly urea class of p38MAPK inhibitors, which binds to the kinase with both slow association and dissociation rates. BIRB -796 has entered clinical trials for the treatment of autoimmune diseases. 
Chemical Structure
 
Chemical Name
1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea. 
SMILES Code
O=C(NC1=C2C=CC=CC2=C(OCCN3CCOCC3)C=C1)NC4=CC(C(C)(C)C)=NN4C5=CC=C(C)C=C5 
Theoretical Analysis
XingMo Cat#:XM379 
Product Name:Doramapimod 
Synonyms:BIRB 796; BIRB796; BIRB-796; Doramapimod. 
CAS#:285983-48-4 
Chemical Formula:C31H37N5O3 
Exact Mass:516.25998 
Molecular Weight:516.6 
Purity:>98% 
Technical Data

Appearance: Solid powder           

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

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