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Description
CAY10505 is a phosphatidylinositol 3-kinase-γ inhibitor , was found to significantly improve acetylcholine-induced endothelium dependent relaxation, serum nitrate and (or) nitrite level, glutathione level, and the vascular endothelial lining in hypertensive rats. CAY10505 , may improve hypertension-associated vascular endothelial dysfunction. Inhibition of PI3Kγ might be a useful approach in the therapeutics of vascular endothelium dysfunction. 
Chemical Structure
 
Chemical Name
(E)-5-((5-(4-fluorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione 
SMILES Code
O=C(NC/1=O)SC1=CC2=CC=C(C3=CC=C(F)C=C3)O2 
Theoretical Analysis
XingMo Cat#:XM087 
Product Name:CAY10505 
Synonyms:CAY10505; CAY 10505; CAY10505 
CAS#:1218777-13-9 
Chemical Formula:C14H8FNO3S 
Exact Mass:289.02089 
Molecular Weight:289.28 
Technical Data

Appearance: Solid powder       

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4o C for short term (days to weeks) or -20o C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

 



WARNING: This product is for research use only, not for human or veterinary use

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