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Description
I-BRD9 is a BRD9 specific inhibitor, identified by scientists at GlaxoSmithKline. I-BRD9 is a potent and selective binder to BRD9 with a pIC50 in a Time-Resolved FRET assay of 7.3. BRD4 was used as a representative member of the BET family for initial selectivity screening, I-BRD9 displayed a pIC50 of 5.3 against this protein. 
Chemical Structure
 
Chemical Name
5-ethyl-4,5-dihydro-4-oxo-N-(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)-7-[3-(trifluoromethyl)phenyl]-thieno[3,2-c]pyridine-2-carboximidamide 
SMILES Code
N=C(C(S1)=CC2=C1C(C3=CC=CC(C(F)(F)F)=C3)=CN(CC)C2=O)NC(CC4)CCS4(=O)=O 
Theoretical Analysis
XingMo Cat#:XM419 
Product Name:I-BRD9 
Synonyms:I-BRD9; I-BRD-9; I-BRD 9. 
CAS#:1714146-59-4 
Chemical Formula:C22H22F3N3O3S2 
Exact Mass:497.1055 
Molecular Weight:497.5512 
Purity:>98% 
Technical Data

Appearance: solid powder                       

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 oC for short term (days to weeks), or -20 oC for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

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