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Description
Roxadustat, also known as ASP1517 and FG-4592, is an HIF α prolyl hydroxylase inhibitor in a cell-free assay. It stabilizes HIF-2 and induces EPO production and stimulates erythropoiesis. Roxadustat transiently and moderately increased endogenous erythropoietin and reduced hepcidin. 
Chemical Structure
 
Chemical Name
(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine 
SMILES Code
O=C(O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC3=CC=CC=C3)C=C2)=O  
Theoretical Analysis
XingMo Cat#:XM073 
Product Name:Roxadustat 
Synonyms:ASP1517; ASP 1517; ASP-1517; FG-4592; FG 4592; FG4592; Roxadustat. 
CAS#:808118-40-3 
Chemical Formula:C19H16N2O5 
Exact Mass:352.10592 
Molecular Weight:352.35 
Technical Data

Appearance: White to off- white solid powder      

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4o C for short term (days to weeks) or -20o C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

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