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Description
GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a family of ubiquitously expressed bromodomain containing proteins. Proteins of the BAZ family are characterized by a carboxy-terminal bromodomain adjacent to a PHD finger and a WACZ motif. In addition four other conserved motifs are typically found in the N-terminus of BAZ family members, namely the LH motif (a leucine-rich helical domain), the ZB2 motif and the BAZ 1 and BAZ 2 motifs. Little is known about the biological function of BAZ2B but it has been suggested to regulate nucleosome mobilization by the ATP-dependent chromatin remodeling factor ISWI. 
Chemical Structure
 
Chemical Name
1-(1-(2-(methylsulfonyl)phenyl)-7-propoxyindolizin-3-yl)ethanone 
SMILES Code
CC(C1=CC(C2=CC=CC=C2S(=O)(C)=O)=C3C=C(OCCC)C=CN13)=O 
Theoretical Analysis
XingMo Cat#:XM068 
Product Name:GSK2801 
Synonyms:GSK2801; GSK-2801; GSK 2801 
CAS#:1619994-68-1 
Chemical Formula:C20H21NO4S 
Exact Mass:371.11913 
Molecular Weight:371.45004 
Technical Data

Appearance: Pale yellow solid powder   

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4o C for short term (days to weeks) or -20o C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

 



WARNING: This product is for research use only, not for human or veterinary use

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