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Description
ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs. ACY-738 induces dramatic increases in α-tubulin acetylation in brain and stimulate mouse exploratory behaviors in novel, but not familiar environments. 
Chemical Structure
 
Chemical Name
N-Hydroxy-2-[(1-phenylcyclopropyl)amino]-5-pyrimidinecarboxamide 
SMILES Code
O=C(C1=CN=C(NC2(C3=CC=CC=C3)CC2)N=C1)NO 
Theoretical Analysis
XingMo Cat#:XM369 
Product Name:ACY-738 
Synonyms:ACY-738; ACY 738; ACY738. 
CAS#:1375465-91-0 
Chemical Formula:C14H14N4O2 
Exact Mass:270.1117 
Molecular Weight:270.292 
Technical Data

Appearance: Solid powder           

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months).

 



WARNING: This product is for research use only, not for human or veterinary use

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