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Description
AZ505 is a potent and highly selective inhibitor of SMYD2 with potential anticancer activity. AZ505 is composed of three distinct moieties: benzooxazinone, cyclohexyl, and dichlorophenethyl substituents. The structure of the ternary complex reveals that a single AZ505 molecule is bound in the peptide binding groove of SMYD2. 
Chemical Structure
 
Chemical Name
N-cyclohexyl-3-((3,4-dichlorophenethyl)amino)-N-(2-((2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethyl)amino)ethyl)propanamide bis(2,2,2-trifluoroacetate) 
SMILES Code
O=C(N(C1CCCCC1)CCNCCC2=C(C(N3)=C(O)C=C2)OCC3=O)CCNCCC4=CC=C(Cl)C(Cl)=C4.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F 
Theoretical Analysis
XingMo Cat#:XM062 
Product Name:AZ-505 2TFA salt 
Synonyms:AZ505 2TFA salt ; AZ 505 2TFA salt ; AZ-505 2TFA salt . 
CAS#:1035227-44-1 
Chemical Formula:C29H38Cl2N4O4 
Exact Mass:576.22701 
Molecular Weight:577.54242 
Technical Data

Appearance: whitesolid powder   

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4℃for short term (days to weeks) or -20℃for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4℃for short term (days to weeks), or -20℃for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

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