GSK990|N/A--Shanghai xingMo Biotechnology

+86-13524779951

sales@xmobio.com

Products

BIOACTIVE COMPOUND

Anti-tumor series

Antithrombotic series

Anti-HCV series

Rheumatism series

Anti-diabetic series

Nervous system series

Others

intermediate

Featured products

Others

This product is in stock，please ask for price.
If you have any question, please send the email to sales@xmobio.com for the availability.We will reply to you as soon as possible.
Shipment: Products are shipped via FedEx Express.

Products

Description

GSK990 is a structurally similar compound which is inactive as an IDH1 inhibitor. GSK990 may be used as a native control to GSK864. SK864 has been shown to be selective in vitro for IDH1 over other classes of proteins (7TMs, ion channels, kinases) and chemoproteomic studies with GSK321, an analog of GSK864, confirm selective binding of IDH1 by this chemical series. GSK864 has a pharmacokinetic profile suitable for in vivo studies. (http://www.thesgc.org/chemical-probes/GSK864).

Chemical Structure

Chemical Name

1-((1H-Imidazol-4-yl)methyl)-5-(1H-pyrrole-2-carbonyl)-N-(m-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide

SMILES Code

O=C(C1=NN(CC2=CNC=N2)C3=C1CN(C(C4=CC=CN4)=O)CC3)NC5=CC=CC(C)=C5

Theoretical Analysis

XingMo Cat#:XM478
Product Name:GSK990
Synonyms:GSK990; GSK-990; GSK 990.
CAS#:N/A
Chemical Formula:C₂₃H₂₃N₇O₂
Exact Mass:429.1913
Molecular Weight:429.484

Technical Data

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months).

WARNING: This product is for research use only, not for human or veterinary use

Tel: +8613524779951 QQ: