+86-13524779951 sales@xmobio.com
Products
  BIOACTIVE COMPOUND
  Anti-tumor series
  Antithrombotic series
  Anti-HCV series
  Rheumatism series
  Anti-diabetic series
  Nervous system series
  Others
  intermediate
  Featured products
  Others

This product is in stock,please ask for price.
If you have any question, please send the email to sales@xmobio.com for the availability.We will reply to you as soon as possible.
Shipment: Products are shipped via FedEx Express.
Products
Description
Ibrutinib, also known as PCI-32765, is a BTK inhibitor, is also a n orally bioavailable small-molecule inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. BTK inhibitor PCI-32765 binds to and inhibits BTK activity, preventing B-cell activation and B-cell-mediated signaling and inhibiting the growth of malignant B cells that overexpress BTK. Ibrutinib was approved by the US FDA on November 13, 2013 for the treatment of mantle cell lymphoma. 
Chemical Structure
 
Chemical Name
(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. 
SMILES Code
C=CC(N1C[C@H](N2N=C(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C(N)N=CN=C52)CCC1)=O 
Theoretical Analysis
XingMo Cat#:XM033 
Product Name:Ibrutinib 
Synonyms:PCI32765; PCI-32765; PCI 32765; Ibrutinib. Brand name: Imbruvica 
CAS#:936563-96-1 
Chemical Formula:C25H24N6O2 
Exact Mass:440.19607 
Molecular Weight:440.49706 
Technical Data

Appearance: white solid powder   

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

Tel: +8613524779951  QQ: 点击这里给我发消息
Email: sales@xmobio.com   Web: www.xmobio.com  沪ICP备17047952号-1
Copyright 2017 Shanghai xingMo Biotechnology Co., Ltd. All rights reserved. Supported by www.hxchem.net