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| Description |
| CCT251236 is a potent and orally active Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen. CCT251236 is orally bioavailable and displays efficacy in a human ovarian carcinoma xenograft model. CCT251236 demonstrated excellent antiproliferative activity against the WM266.4 cell line (pGI50 = 7.92 ± 0.10, GI50 = 12 nM, n =11). |
| Chemical Structure |
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| Chemical Name |
| N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)-2-(2-(pyrrolidin-1-yl)ethoxy)quinoline-6-carboxamide |
| SMILES Code |
| O=C(C1=CC(C=CC(OCCN2CCCC2)=N3)=C3C=C1)NC4=CC(NC(C5=CC(OCCO6)=C6C=C5)=O)=CC=C4C |
| Theoretical Analysis |
XingMo Cat#:XM343
Product Name:CCT251236
Synonyms:CCT251236; CCT-251236; CCT 251236.
CAS#:1693731-40-6
Chemical Formula:C32H32N4O5
Exact Mass:552.2373
Molecular Weight:552.631
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| Technical Data |
WARNING: This product is for research use only, not for human or veterinary use
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