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Description
MK0752 is a synthetic small molecule with potential antineoplastic activity. MK0752 inhibits the Notch signaling pathway, which may result in induction of growth arrest and apoptosis in tumor cells in which the Notch signaling pathway is overactivated. The Notch signaling pathway plays an important role in cell-fate determination, cell survival, and cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). 
Chemical Structure
 
Chemical Name
3-((1r,4s)-4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid. 
SMILES Code
O=C(O)CC[C@H]1CC[C@](C2=CC(F)=CC=C2F)(S(=O)(C3=CC=C(Cl)C=C3)=O)CC1 
Theoretical Analysis
XingMo Cat#:XM197 
Product Name:MK-0752 
Synonyms:MK0752. 
CAS#:471905-41-6 
Chemical Formula:C21H21ClF2O4S 
Exact Mass:442.08171 
Molecular Weight:442.9 
Technical Data

Appearance: Solid powder               

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4oC for short term (days to weeks), or -20oC for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

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