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| 产品描述 |
| CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. Based on the chemistry of SP600125, another anthrapyrazolone inhibitor of JNK, CC-401 competitively binds the ATP binding site of JNK, resulting in inhibition of the phosphorylation of the N-terminal activation domain of transcription factor c-Jun; decreased transcription activity of c-Jun; and a variety of cellular effects including decreased cellular proliferation. |
| 化学结构 |
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| 化学名称 |
| 3-(3-(2-(piperidin-1-yl)ethoxy)phenyl)-5-(1H-1,2,4-triazol-5-yl)-1H-indazole |
| SMILES Code |
| C1(C2=CC=CC(OCCN3CCCCC3)=C2)=NNC4=C1C=C(C5=NC=NN5)C=C4 |
| 基本信息 |
产品编号:XM121
产品名称:CC-401
别名:CC401; CC 401; CC-401.
CAS#:862832-38-0 (free base)
分子式:C22H24N6O
精确分子量:388.20116
分子量:388.46
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| 物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用，不能给病人提供。
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