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| 产品描述 |
| M7583 is a potent, orally administered, highly selective, adenosine triphosphate (ATP)-competitive, second generation, irreversible inhibitor of BTK. Kinase specificity has been determined in vitro using the Merck Millipore Kinase Profiler panel. Only 3 kinases (Blk, BMX, and Txk) had IC50s within a 10-fold range of BTK (BTK IC50 = 18.5 nM; Blk IC50 = 77 nM; BMX IC50= 5 nM; Txk IC50 = 62 nM). |
| 化学结构 |
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| 化学名称 |
| 1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)-4-fluoropiperidin-1-yl)prop-2-en-1-one, 1-(4-{[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-ylamino]methyl}-4-fluoropiperidin-1-yl)prop-2-en-1 |
| 基本信息 |
产品编号:XM800
产品名称:TL-895, M7583
别名:M7583,M-7583
CAS#:1415823-49-2
分子式:C25H26FN5O2
分子量:447.512
纯度:98%
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| 物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用，不能给病人提供。
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