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产品描述 |
FT-4101 is a potent, selective, oral small molecule inhibitor of fatty acid synthase (FASN), a key enzyme in the de novo lipogenesis (DNL) pathway responsible for hepatic lipid composition. Through FASN inhibition, FT-4101 is expected to reduce the rate of new fat production, thereby systemically affecting lipid accumulation in the liver and potentially mitigating the cellular damage, inflammation, and fibrosis that characterizes the pathology of nonalcoholic steatohepatitis (NASH). FT-4101 is being evaluated in a randomized, double-blind, placebo-controlled Phase 2 study to evaluate the safety, tolerability, pharmacokinetics/pharmacodynamics (PK/PD) and efficacy of FT-4101 in adult patients with NASH. |
化学名称 |
(4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone |
基本信息 |
产品编号:XM798 产品名称:FT-4101 别名:FT-4101,FT4101 CAS#:2230273-76-2 分子式:C23H23FN4O3 分子量:422.459 纯度:98%
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物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品,适于常温或冰袋运输。
储存条件: 低温,干燥,避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用,不能给病人提供。
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