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产品描述 |
GS-5829 is a potent and selective BET inhibitor. The bromodomain and extraterminal (BET) protein Brd4 recruits transcriptional regulatory complexes to acetylated chromatin. While Brd4 is considered to be a general transcriptional regulator, pharmacological inhibition of BET proteins shows therapeutic activity in a variety of different pathologies, particularly in models of cancer and inflammation. |
化学结构 |
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化学名称 |
[2-cyclopropyl-6-(3,5-dimethyl-1,2-oxazol-4-yl)- 1H-benzimidazol-4-yl]di(pyridin-2-yl)methanol |
基本信息 |
产品编号:XM779 产品名称:Alobresib (GS-5829) 别名:Alobresib ,GS-5829,GS5829 CAS#:1637771-14-2 分子式:C26H23N5O2 分子量:437.5 纯度:>98%
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物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品,适于常温或冰袋运输。
储存条件: 低温,干燥,避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用,不能给病人提供。
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