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| 产品描述 |
| LYC-55716 (Cintirorgon) is a first-in-class, selective, orally active RORγ agonist, modulates expression of genes that promote immune responses; reduces PD-1 expression in vitro and in vivo after adoptive cell transfer, relieves PD-1/PD-L1 inhibition of proliferation and IFNγ; significantly augments anti-tumor activity of doxorubicin, results in immune-dependent decreased tumor growth and enhanced survival in preclinical models of cancer. |
| 化学结构 |
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| 化学名称 |
| (S)-3-(6-(3-(difluoromethoxy)-5-fluorophenyl)-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)-2,2-dimethylpropanoic acid |
| 基本信息 |
产品编号:XM768
产品名称:LYC-55716
别名:LYC-55716,LYC55716
CAS#:2055536-64-4
分子式:C27H23F6NO6S
精确分子量:603.532
分子量:603.53
纯度:98%
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| 物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用，不能给病人提供。
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