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产品类别
  活性分子
  抗癌类
  抗血栓类
  丙肝类
  风湿类
  糖尿病类
  神经系统类
  其他
  中间体
  特色产品
  其他

产品介绍
产品描述
CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM. It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM). The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin. 
化学结构
 
化学名称
3-(5-fluoro-4-(4-methyl-2-(methylamino)thiazol-5-yl)pyrimidin-2-ylamino)benzene sulfonamide 
SMILES Code
O=S(C1=CC=CC(NC2=NC=C(F)C(C3=C(C)N=C(NC)S3)=N2)=C1)(N)=O 
基本信息
产品编号:XM744 
产品名称:CDKI-73 
别名:CDKI-73; CDKI 73; CDKI73 
CAS#:1421693-22-2 
分子式:C15H15FN6O2S2 
精确分子量:394.0682 
分子量:394.44 
纯度:>98% 
物化性质
Appearance:
Solid powder
Purity:
>98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility:
Soluble in DMSO
Shelf Life:
>2 years if stored properly
Drug Formulation:
This drug may be formulated in DMSO
Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
 



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