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| 产品描述 |
| RO4987655, also known as CH4987655, is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity. MEK inhibitor RO4987655 binds to and inhibits MEK, which may result in the inhibition of MEK-dependent cell signaling and the inhibition of tumor cell proliferation. MEK, a dual specificity threonine/tyrosine kinase, is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth; constitutive activation of this pathway has been implicated in many cancers. |
| 化学结构 |
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| 化学名称 |
| 3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-5-((3-oxo-1,2-oxazinan-2-yl)methyl)benzamide |
| SMILES Code |
| O=C(NOCCO)C1=CC(CN2OCCCC2=O)=C(F)C(F)=C1NC3=CC=C(I)C=C3F |
| 基本信息 |
产品编号:XM097
产品名称:RO4987655
别名:RO4987655; RO-4987655; RO 4987655; CH4987655; CH-4987655; CH 4987655.
CAS#:874101-00-5
分子式:C20H19F3IN3O5
精确分子量:565.03215
分子量:565.28
纯度:>98%
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| 物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存
药物剂型: 可以DMSO 配制。 |
该产品只供科研使用，不能给病人提供。
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