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产品描述 |
ETC-206 was identified with MNK1/2 IC50 values of 0.064/0.086 uM and an IC50 value for HeLa cell proliferation of 0.362 uM .ETC-206 also showed antitumor effects in a xenograft mouse model of BC-CML bearing K562 elF4E,and in combination with dasatinib(2.5 mg/kg) totally reduced tumor growth.A phase I trial in healthy volunteers has recently been completed. |
化学结构 |
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化学名称 |
4-(6-(4- (morpholine-4-carbonyl)phenyl)imidazo[l,2-a]pyridin-3-yl)benzonitrile |
基本信息 |
产品编号:XM726 产品名称:ETC-206 别名:ETC-206, ETC206 CAS#:1464151-33-4 分子式:C25H20N4O2 分子量:408.459 纯度:>98%
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物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品,适于常温或冰袋运输。
储存条件: 低温,干燥,避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用,不能给病人提供。
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