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产品描述 |
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, CC-90003 inhibits ERK activity, and prevents the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival. |
化学结构 |
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化学名称 |
N-{2-[2-(2-Methoxy-5-methyl-pyridin-4-ylamino)-5-trifluoromethyl-pyrimidin-4-ylamino]-5-methyl-phenyl}-acrylamide |
基本信息 |
产品编号:XM723 产品名称:CC-90003 别名:CC-90003,CC90003 CAS#:1621999-82-3 分子式:C22H21F3N6O2 精确分子量:458.44 分子量:458.17 纯度:>98%
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物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品,适于常温或冰袋运输。
储存条件: 低温,干燥,避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用,不能给病人提供。
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