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| 产品描述 |
| ASP5878 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR), with potential antineoplastic activity. Upon oral administration, FGFR inhibitor ASP5878 binds to and inhibits FGFR, which results in the inhibition of FGFR-mediated signal transduction pathways. This inhibits proliferation in FGFR-overexpressing tumor cells. FGFR, a family of receptor tyrosine kinases upregulated in many tumor cell types, plays a key role in cellular proliferation and survival. |
| 化学结构 |
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| 化学名称 |
| 2-{4-[5-(2,6-Difluoro-3,5-dimethoxy-benzyloxy)-pyrimidin-2-ylamino]-pyrazol-1-yl}-ethanol |
| 基本信息 |
产品编号:XM715
产品名称:ASP-5878
别名:ASP-5878,ASP5878
CAS#:1453208-66-6
分子式:C18H19F2N5O4
精确分子量:407.14
分子量:407.37
纯度:>98%
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| 物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用，不能给病人提供。
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