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| 产品描述 |
| Molidustat, also known as BAY 85-3934, is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells. Phase I data have shown that inhibition of HIF-PH by Molidustat results in an increase in endogenous production of EPO. Molidustat is currently clinical trials at Bayer for the treatment of patients suffering from renal anemia due to chronic kidney disease. |
| 化学结构 |
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| 化学名称 |
| 2-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-3(2H)-one |
| SMILES Code |
| O=C1N(C2=NC=NC(N3CCOCC3)=C2)NC=C1N4N=NC=C4 |
| 基本信息 |
产品编号:XM273
产品名称:Molidustat
CAS#:1154028-82-6
分子式:C13H14N8O2
精确分子量:314.12397
分子量:314.3
纯度:>98%
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| 物化性质 |
外观: 白色或类白色固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限: 3 年 -20℃ 固体储存 2 年 -80℃ 溶液储存 |
该产品只供科研使用，不能给病人提供。
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