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产品描述 |
ICI-118551, also known as ICI-118,551, is a selective beta-2 (β2) adrenergic receptor antagonist. ICI-118551 binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor. The compound was developed by Imperial Chemical Industries, which was acquired by AkzoNobel in 2008. ICI-118,551 has no known therapeutic use in humans although it has been used widely in research to understand the action of the β2 adrenergic receptor, as few other specific antagonists for this receptor are known. |
化学结构 |
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化学名称 |
(2R,3S)-3-(isopropylamino)-1-((7-methyl-2,3-dihydro-1H-inden-4-yl)oxy)butan-2-ol hydrochloride |
SMILES Code |
C[C@H](NC(C)C)[C@@H](O)COC1=CC=C(C)C2=C1CCC2.[H]Cl |
基本信息 |
产品编号:XM020 产品名称:ICI-118551 HCl CAS#:72795-01-8 (HCl salt); 72795-19-8 (free base). 分子式:C17H28ClNO2 精确分子量:313.87 分子量:313.87
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物化性质 |
外观: 类白色固体粉末状
运输信息: 非危险化学品,适于常温或冰袋运输。
储存条件: 低温,干燥,避光。
溶解性: 溶于DMSO, 不溶于水
储存期限: 3 年 -20℃ 固体储存 2 年 -80℃ 溶液储存 |
该产品只供科研使用,不能给病人提供。
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