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产品描述 |
GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a family of ubiquitously expressed bromodomain containing proteins. Proteins of the BAZ family are characterized by a carboxy-terminal bromodomain adjacent to a PHD finger and a WACZ motif. In addition four other conserved motifs are typically found in the N-terminus of BAZ family members, namely the LH motif (a leucine-rich helical domain), the ZB2 motif and the BAZ 1 and BAZ 2 motifs. Little is known about the biological function of BAZ2B but it has been suggested to regulate nucleosome mobilization by the ATP-dependent chromatin remodeling factor ISWI. |
化学结构 |
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化学名称 |
1-(1-(2-(methylsulfonyl)phenyl)-7-propoxyindolizin-3-yl)ethanone |
SMILES Code |
CC(C1=CC(C2=CC=CC=C2S(=O)(C)=O)=C3C=C(OCCC)C=CN13)=O |
基本信息 |
产品编号:XM068 产品名称:GSK2801 别名:GSK2801; GSK-2801; GSK 2801 CAS#:1619994-68-1 分子式:C20H21NO4S 精确分子量:371.11913 分子量:371.45004
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物化性质 |
外观: 淡黄色固体粉末
纯度: >98%
运输信息: 非危险化学品,适于常温或冰袋运输。
储存条件: 低温,干燥,避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用,不能给病人提供。
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