| 产品描述 |
| ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs. ACY-738 induces dramatic increases in α-tubulin acetylation in brain and stimulate mouse exploratory behaviors in novel, but not familiar environments. |
| 化学结构 |
 |
| 化学名称 |
| N-Hydroxy-2-[(1-phenylcyclopropyl)amino]-5-pyrimidinecarboxamide |
| SMILES Code |
| O=C(C1=CN=C(NC2(C3=CC=CC=C3)CC2)N=C1)NO |
| 基本信息 |
产品编号:XM369
产品名称:ACY-738
别名:ACY-738; ACY 738; ACY738.
CAS#:1375465-91-0
分子式:C14H14N4O2
精确分子量:270.1117
分子量:270.292
|
| 物化性质 |
外观: 白色或类白色固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
