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| 产品描述 |
| Spebrutinib, also known as AVL-292 or CC-292, is an orally bioavailable, selective inhibitor of BrutonÂ’s agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL-292 targets and covalently binds to BTK, thereby preventing its activity. By irreversibly inhibiting BTK, administration of this agent may lead to an inhibition of B cell receptor (BCR) signaling and may inhibit cell proliferation of B-cell malignancies. |
| 化学结构 |
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| 化学名称 |
| N-(3-((5-fluoro-2-((4-(2-methoxyethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide |
| SMILES Code |
| C=CC(NC1=CC=CC(NC2=NC(NC3=CC=C(OCCOC)C=C3)=NC=C2F)=C1)=O |
| 基本信息 |
产品编号:XM006
产品名称:Spebrutinib (AVL-292)
别名:CC292; CC-292; CC 292; AVL292; AVL-292; AVL 292.
CAS#:1202757-89-8
分子式:C22H22FN5O3
精确分子量:423.17067
分子量:423.44
纯度:>98%
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| 物化性质 |
外观: 白色固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3 年-20℃ 固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用，不能给病人提供。
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