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| 产品描述 |
| MK2206 is a Akt inhibitor, is also an orally bioavailable allosteric inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor MK2206 binds to and inhibits the activity of Akt in a non-ATP competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. |
| 化学结构 |
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| 化学名称 |
| 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-8,9-dihydro-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride |
| SMILES Code |
| O=C1NN=C2C3=CC(C4=CC=CC=C4)C(C5=CC=C(C6(N)CCC6)C=C5)N=C3C=CN21.[H]Cl.[H]Cl |
| 基本信息 |
产品编号:XM055
产品名称:MK-2206 2HCl
别名:MK2206; MK-2206; MK 2206; MK2206 dihydrochloride; MK2206 HCl.
CAS#:1032350-13-2 (2HCl), 1032349-77-1 (HCl);1032349-93-1 (free base).
分子式:C25H25Cl2N5O
精确分子量:481.14362
分子量:409.48483
纯度:>98%
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| 物化性质 |
外观: 黄固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃溶液储存 |
该产品只供科研使用，不能给病人提供。
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