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| 产品描述 |
| PF-04217903 is a MET tyrosine kinase inhibitor, is also an orally bioavailabe, small-molecule tyrosine kinase inhibitor of the proto-oncogene c-Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met inhibitor PF-04217903 selectively binds to and inhibits c-Met, disrupting the c-Met signaling pathway, which may result in the inhibition of tumor cell growth, migration and invasion of tumor cells, and the induction of death in tumor cells expressing c-Met. |
| 化学结构 |
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| 化学名称 |
| 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol |
| SMILES Code |
| OCCN1N=CC(C2=CN=C3C(N(CC4=CC=C5N=CC=CC5=C4)N=N3)=N2)=C1 |
| 基本信息 |
产品编号:XM471
产品名称:PF-04217903
别名:PF04217903; PF 04217903; PF-04217903; PF4217903; PF-4217903; PF 4217903.
CAS#:956905-27-4 (free base); 956906-93-7 (mesylate)
分子式:C19H16N8O
精确分子量:372.14471
分子量:372.38
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| 物化性质 |
外观: 白色固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用，不能给病人提供。
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