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产品描述 |
AS-604850 is a selective PI3Kγ inhibitor, which significantly reduced the number of infiltrated leukocytes in the CNS and ameliorated the clinical symptoms of EAE mice. Treatment with this PI3Kγ inhibitor enhanced myelination and axon number in the spinal cord of EAE mice. PI3Kγ contributes to development of autoimmune CNS inflammation and that PI3Kγ blockade may provide a great potential for treating patients with MS. |
化学结构 |
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化学名称 |
(Z)-5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methylene)thiazolidine-2,4-dione |
SMILES Code |
O=C(NC/1=O)SC1=C/C2=CC=C(OC(F)(F)O3)C3=C2 |
基本信息 |
产品编号:XM004 产品名称:AS-604850 别名:AS604850; AS 604850; AS-604850. CAS#:648449-76-7 分子式:C11H5F2NO4S 精确分子量:284.99073 分子量:285.22 纯度:>98%
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物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品,适于常温环境下运输。
储存条件: 低温,干燥,避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3 年-20℃固体储存
2 年 -80℃溶液储存 |
该产品只供科研使用,不能给病人提供。
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