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| 产品描述 |
| Erdafitinib, also known as JNJ-42756493, is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Upon oral administration, JNJ-42756493 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways and thus the inhibition of tumor cell proliferation and tumor cell death in FGFR-overexpressing tumor cells. FGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival. |
| 化学结构 |
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| 化学名称 |
| N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine |
| SMILES Code |
| CC(NCCN(C1=CC(OC)=CC(OC)=C1)C2=CC=C3N=CC(C4=CN(C)N=C4)=NC3=C2)C |
| 基本信息 |
产品编号:XM022
产品名称:Erdafitinib (JNJ-42756493)
别名:JNJ-42756493; JNJ 42756493; JNJ42756493; Erdafitinib
CAS#:1346242-81-6
分子式:C25H30N6O2
精确分子量:446.24302
分子量:446.55
纯度:>98%
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| 物化性质 |
外观: 类白色固体
纯度: >98%
运输信息: 非危险化学品，适于常温环境下运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3 年-20℃ 固体储存
2 年-80℃ 溶液储存 |
该产品只供科研使用，不能给病人提供。
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