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| 产品描述 |
| Vismodegib, also known as GDC-0449 or RG3616, is a hedgehog antagonist, is also a n orally bioavailable small molecule with potential antineoplastic activity. Hedgehog antagonist GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. |
| 化学结构 |
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| 化学名称 |
| 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide |
| SMILES Code |
| O=C(NC1=CC=C(Cl)C(C2=NC=CC=C2)=C1)C3=CC=C(S(=O)(C)=O)C=C3Cl |
| 基本信息 |
产品编号:XM225
产品名称:Vismodegib
别名:GDC0449; GDC 0449; GDC-0449; RG3616; RG 3616; RG-3616. Vismodegib; trade name: Erivedge.
CAS#:879085-55-9
分子式:C19H14Cl2N2O3S
精确分子量:420.01022
分子量:421.3
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| 物化性质 |
外观: 白色固体粉末
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用，不能给病人提供。
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