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产品描述 |
AS605240 is a selective PI3Kgamma inhibitor, has been proved effective on several inflammatory diseases. Orally administration of AS605240 significantly prevented lung inflammation and reduced collagen deposition. AS605240 also inhibited augmented expression of TNF-alpha and IL-1beta induced by bleomycin instillation. AS605240 may be a useful in treating inflammation diseases. AS605240 may represent a promising novel agent for the future therapy of pulmonary fibrosis. |
化学结构 |
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化学名称 |
(E)-5-(quinoxalin-6-ylmethylene)thiazolidine-2,4-dione |
SMILES Code |
O=C(NC/1=O)SC1=CC2=CC=C3N=CC=NC3=C2 |
基本信息 |
产品编号:XM159 产品名称:AS-605240 别名:AS 605240; AS605240; AS-605240. CAS#:648450-29-7 分子式:C12H7N3O2S 精确分子量:257.0259 分子量:257.27
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物化性质 |
外观: 固体粉末
纯度: >98%
运输信息: 非危险化学品,适于常温或冰袋运输。
储存条件: 低温,干燥,避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
该产品只供科研使用,不能给病人提供。
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