| 产品描述 |
| CX-6258 is a pan-Pim kinases inhibitor with excellent biochemical potency and kinase selectivity. CX-6258 exhibited in vitro synergy with chemotherapeutics and robust in vivo efficacy in two Pim kinases driven tumor models. Inhibition of Pim kinases is expected to have a beneficial effect as cancer therapy. |
| 化学结构 |
 |
| 化学名称 |
| (E)-5-chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2-one |
| SMILES Code |
| O=C1NC2=C(C=C(Cl)C=C2)/C1=CC3=CC=C(C4=CC=CC(C(N5CCN(C)CCC5)=O)=C4)O3 |
| 基本信息 |
产品编号:XM147
产品名称:CX-6258
别名:CX6258; CX-6258; CX 6258.
CAS#:1202916-90-2 (free base)
分子式:C26H24ClN3O3
精确分子量:461.15062
分子量:461.94
|
| 物化性质 |
外观: 淡黄色固体
纯度: >98%
运输信息: 非危险化学品，适于常温或冰袋运输。
储存条件: 低温，干燥，避光。
溶解性: 溶于DMSO, 不溶于水
储存期限:3年 -20℃固体储存
2 年 -80℃ 溶液储存 |
